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CpG site DNA methylation patterns reveal a novel regulatory element in the mouse prion protein gene
The cellular isoform of the prion protein (PrP(C)) plays critical roles in the development of prion disorders. Although PrP mRNA is ubiquitously present in a tissue-specific manner, the DNA methylation of PrP gene (Prnp) is still unknown. In this study, we demonstrated that the CpG island (CGI, posi...
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| Publicado no: | J Vet Med Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Japanese Society of Veterinary Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289245/ https://ncbi.nlm.nih.gov/pubmed/27666463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.16-0390 |
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