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CpG site DNA methylation patterns reveal a novel regulatory element in the mouse prion protein gene
The cellular isoform of the prion protein (PrP(C)) plays critical roles in the development of prion disorders. Although PrP mRNA is ubiquitously present in a tissue-specific manner, the DNA methylation of PrP gene (Prnp) is still unknown. In this study, we demonstrated that the CpG island (CGI, posi...
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| Vydáno v: | J Vet Med Sci |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Japanese Society of Veterinary Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289245/ https://ncbi.nlm.nih.gov/pubmed/27666463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.16-0390 |
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