Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation and maturation of vascular smooth muscle cells (vSMC). In adult Notch3(–/–) mice distal arteries exhibit st...

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Detalhes bibliográficos
Main Authors: Domenga, Valérie, Fardoux, Peggy, Lacombe, Pierre, Monet, Marie, Maciazek, Jacqueline, Krebs, Luke T., Klonjkowski, Bernard, Berrou, Eliane, Mericskay, Matthias, Li, Zhen, Tournier-Lasserve, Elisabeth, Gridley, Thomas, Joutel, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC528893/
https://ncbi.nlm.nih.gov/pubmed/15545631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.308904
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