Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation and maturation of vascular smooth muscle cells (vSMC). In adult Notch3(–/–) mice distal arteries exhibit st...

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Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Domenga, Valérie, Fardoux, Peggy, Lacombe, Pierre, Monet, Marie, Maciazek, Jacqueline, Krebs, Luke T., Klonjkowski, Bernard, Berrou, Eliane, Mericskay, Matthias, Li, Zhen, Tournier-Lasserve, Elisabeth, Gridley, Thomas, Joutel, Anne
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 2004
Fag:	Research Communications
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC528893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15545631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.308904
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