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Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

Abstract Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic paradigm of small vessel disease (SVD) caused by NOTCH3 mutations that stereotypically lead to the vascular accumulation of NOTCH3 around smooth muscle cells and pericytes. Whit...

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Váldodahkkit: Rikesh M. Rajani, Julien Ratelade, Valérie Domenga-Denier, Yoshiki Hase, Hannu Kalimo, Raj N. Kalaria, Anne Joutel
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2019-11-01
Ráidu:Acta Neuropathologica Communications
Fáttát:
Liŋkkat:http://link.springer.com/article/10.1186/s40478-019-0844-x
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