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LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis
Wnt signaling, which is mediated by LEF1/TCF transcription factors, has been placed upstream of the Notch pathway in vertebrate somitogenesis. Here, we examine the molecular basis for this presumed hierarchy and show that a targeted mutation of Lef1, which abrogates LEF1 function and impairs the act...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC528889/ https://ncbi.nlm.nih.gov/pubmed/15545629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1249504 |
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