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FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1(−/−) mice

Lymphoid enhancer factor (LEF1), a nuclear mediator of Wnt signaling, is required for the formation of organs that depend on inductive interactions between epithelial and mesenchymal tissues. In previous tissue recombination experiments with normal and Lef1(−/−) tooth germs, we found that the effect...

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Main Authors: Kratochwil, Klaus, Galceran, Juan, Tontsch, Sabine, Roth, Wera, Grosschedl, Rudolf
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC187508/
https://ncbi.nlm.nih.gov/pubmed/12502739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1035602
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