Wnt3a(−/−)-like phenotype and limb deficiency in Lef1(−/−)Tcf1(−/−) mice
Members of the LEF-1/TCF family of transcription factors have been implicated in the transduction of Wnt signals. However, targeted gene inactivations of Lef1, Tcf1, or Tcf4 in the mouse do not produce phenotypes that mimic any known Wnt mutation. Here we show that null mutations in both Lef1 and Tc...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
1999
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10090727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.6.709 |
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