Wnt3a(−/−)-like phenotype and limb deficiency in Lef1(−/−)Tcf1(−/−) mice

Members of the LEF-1/TCF family of transcription factors have been implicated in the transduction of Wnt signals. However, targeted gene inactivations of Lef1, Tcf1, or Tcf4 in the mouse do not produce phenotypes that mimic any known Wnt mutation. Here we show that null mutations in both Lef1 and Tc...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Galceran, Juan, Fariñas, Isabel, Depew, Michael J., Clevers, Hans, Grosschedl, Rudolf
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1999
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10090727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.6.709
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