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Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin

In skin, multipotent stem cells generate the keratinocytes of the epidermis, sebaceous gland, and hair follicles. In this paper, we show that Tcf3 and Lef1 control these differentiation lineages. In contrast to Lef1, which requires Wnt signaling and stabilized β-catenin to express the hair-specific...

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Detalhes bibliográficos
Main Authors: Merrill, Bradley J., Gat, Uri, DasGupta, Ramanuj, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312726/
https://ncbi.nlm.nih.gov/pubmed/11445543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.891401
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