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TBK1: a new player in ALS linking autophagy and neuroinflammation

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder affecting motor neurons, resulting in progressive muscle weakness and death by respiratory failure. Protein and RNA aggregates are a hallmark of ALS pathology and are thought to contribute to ALS by impairing axonal tra...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Oakes, James A., Davies, Maria C., Collins, Mark O.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288885/
https://ncbi.nlm.nih.gov/pubmed/28148298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0287-x
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