Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation

Development of an immune or autoimmune response involves T-cell activation in lymphoid organs and subsequent migration to peripheral tissues. Here we show that T-cell-specific ablation of the kinase TBK1 promotes T-cell activation but causes retention of effector T cells in the draining lymph node i...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yu, Jiayi, Zhou, Xiaofei, Chang, Mikyoung, Nakaya, Mako, Chang, Jae-Hoon, Xiao, Yichuan, William Lindsey, J., Dorta-Estremera, Stephanie, Cao, Wei, Zal, Anna, Zal, Tomasz, Sun, Shao-Cong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302769/
https://ncbi.nlm.nih.gov/pubmed/25606824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7074
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