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Mutagenesis of NosM Leader Peptide Reveals Important Elements in Nosiheptide Biosynthesis

Nosiheptide, a typical member of the ribosomally synthesized and posttranslationally modified peptides (RiPPs), exhibits potent activity against multidrug-resistant Gram-positive bacterial pathogens. The precursor peptide of nosiheptide (NosM) is comprised of a leader peptide with 37 amino acids and...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Jin, Liang, Wu, Xuri, Xue, Yanjiu, Jin, Yue, Wang, Shuzhen, Chen, Yijun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288820/
https://ncbi.nlm.nih.gov/pubmed/27913416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02880-16
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