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Follow the leader: The use of leader peptides to guide natural product biosynthesis

The avalanche of genomic information in the past decade has revealed that natural product biosynthesis using the ribosomal machinery is much more widespread than originally anticipated. Nearly all of these compounds are crafted through posttranslational modifications of a larger precursor peptide th...

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Detalhes bibliográficos
Main Authors: Oman, Trent J., van der Donk, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799897/
https://ncbi.nlm.nih.gov/pubmed/20016494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.286
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