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Chimeric Leader Peptides for the Generation of Non-Natural Hybrid RiPP Products

[Image: see text] Combining biosynthetic enzymes from multiple pathways is an attractive approach for producing molecules with desired structural features; however, progress has been hampered by the incompatibility of enzymes from unrelated pathways and intolerance toward alternative substrates. Rib...

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Dettagli Bibliografici
Pubblicato in:ACS Cent Sci
Autori principali: Burkhart, Brandon J., Kakkar, Nidhi, Hudson, Graham A., van der Donk, Wilfred A., Mitchell, Douglas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2017
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492250/
https://ncbi.nlm.nih.gov/pubmed/28691075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00141
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