Activation of the complement cascade enhances motility of leukemic cells by downregulating expression of HO-1

As a crucial arm of innate immunity, the complement cascade (ComC) is involved both in mobilization of normal hematopoietic stem/progenitor cells (HSPCs) from bone marrow (BM) into peripheral blood and in their homing to BM. Despite the fact that ComC cleavage fragments alone do not chemoattract nor...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Abdelbaset-Ismail, A, Borkowska-Rzeszotek, S, Kubis, E, Bujko, K, Brzeźniakiewicz-Janus, K, Bolkun, L, Kloczko, J, Moniuszko, M, Basak, G W, Wiktor-Jedrzejczak, W, Ratajczak, M Z
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288274/
https://ncbi.nlm.nih.gov/pubmed/27451975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.198
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