Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells

We recently reported that normal hematopoietic stem cells express functional pituitary sex hormone (SexH) receptors. Here we report for the first time that pituitary-secreted gonadotrophins stimulate migration, adhesion, and proliferation of several human myeloid and lymphoid leukemia cell lines. Si...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Abdelbaset-Ismail, Ahmed, Borkowska, Sylwia, Janowska-Wieczorek, Anna, Tonn, Torsten, Rodriguez, Cesar, Moniuszko, Marcin, Bolkun, Lukasz, Koloczko, Janusz, Eljaszewicz, Andrzej, Ratajczak, Janina, Ratajczak, Mariusz Z., Kucia, Magda
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823088/
https://ncbi.nlm.nih.gov/pubmed/26701888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6698
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