Bioactive Phospholipids Enhance Migration and Adhesion of Human Leukemic Cells by Inhibiting Heme Oxygenase 1 (HO-1) and Inducible Nitric Oxygenase Synthase (iNOS) in a p38 MAPK-Dependent Manner

Bioactive phospholipids, including sphingosine-1-phosphate (S1P), ceramide-1-phosphate (C1P), lysophosphatidylcholine (LPC), and its derivative lysophosphatidic acid (LPA), have emerged as important mediators regulating the trafficking of normal and cancer cells. While the role of S1P in regulating...

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Udgivet i:Stem Cell Rev
Main Authors: Abdelbaset-Ismail, Ahmed, Cymer, Monika, Borkowska-Rzeszotek, Sylwia, Brzeźniakiewicz-Janus, Katarzyna, Rameshwar, Pranela, Kakar, Sham S., Ratajczak, Janina, Ratajczak, Mariusz Z.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366663/
https://ncbi.nlm.nih.gov/pubmed/30302660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-018-9853-6
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