miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways

MicroRNAs (miRNAs) are attractive therapeutic targets for various therapy-resistant tumors. However, the association between miRNA and BRAF inhibitor resistance in melanoma remains to be elucidated. We used microarray analysis to comprehensively study the miRNA expression profiling of vemurafenib re...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Sun, Xiaoyan, Li, Jun, Sun, Yanhong, Zhang, Yi, Dong, Liyun, Shen, Chen, Yang, Liu, Yang, Ming, Li, Yan, Shen, Guanxin, Tu, Yating, Tao, Juan
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288205/
https://ncbi.nlm.nih.gov/pubmed/27448964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10669
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