miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways

MicroRNAs (miRNAs) are attractive therapeutic targets for various therapy-resistant tumors. However, the association between miRNA and BRAF inhibitor resistance in melanoma remains to be elucidated. We used microarray analysis to comprehensively study the miRNA expression profiling of vemurafenib re...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sun, Xiaoyan, Li, Jun, Sun, Yanhong, Zhang, Yi, Dong, Liyun, Shen, Chen, Yang, Liu, Yang, Ming, Li, Yan, Shen, Guanxin, Tu, Yating, Tao, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288205/
https://ncbi.nlm.nih.gov/pubmed/27448964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10669
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