Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence

CarD is an essential RNA polymerase (RNAP) interacting protein in Mycobacterium tuberculosis that stimulates formation of RNAP-promoter open complexes. CarD plays a complex role in M. tuberculosis growth and virulence that is not fully understood. Therefore, to gain further insight into the role of...

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Udgivet i:J Bacteriol
Main Authors: Garner, Ashley L., Rammohan, Jayan, Huynh, Jeremy P., Onder, Lucas M., Chen, James, Bae, Brian, Jensen, Drake, Weiss, Leslie A., Manzano, Ana Ruiz, Darst, Seth A., Campbell, Elizabeth A., Nickels, Bryce E., Galburt, Eric A., Stallings, Christina L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287406/
https://ncbi.nlm.nih.gov/pubmed/27920294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00698-16
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