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Scalable C-H Oxidation with Copper: Synthesis of Polyoxypregnanes

Steroids bearing C12 oxidations are widespread in nature yet only one preparative chemical method addresses this challenge in a low-yielding and not fully understood fashion: Schönecker's Cu-mediated oxidation. This work shines new light onto this powerful C–H oxidation method through mechanist...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: See, Yi Yang, Herrmann, Aaron T., Aihara, Yoshinori, Baran, Phil S.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287264/
https://ncbi.nlm.nih.gov/pubmed/26466196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b09463
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