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The C1 and C2 domains of blood coagulation factor VIII mediate its endocytosis by dendritic cells
The development of inhibitory antibodies to therapeutic factor VIII is the major complication of replacement therapy in patients with hemophilia A. The first step in the initiation of the anti-factor VIII immune response is factor VIII interaction with receptor(s) on antigen-presenting cells, follow...
Tallennettuna:
| Julkaisussa: | Haematologica |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Ferrata Storti Foundation
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286935/ https://ncbi.nlm.nih.gov/pubmed/27758819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.148502 |
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