Herpes Simplex Virus 1 UL41 Protein Suppresses the IRE1/XBP1 Signal Pathway of the Unfolded Protein Response via Its RNase Activity

During viral infection, accumulation of viral proteins can cause stress in the endoplasmic reticulum (ER) and trigger the unfolded protein response (UPR) to restore ER homeostasis. The inositol-requiring enzyme 1 (IRE1)-dependent pathway is the most conserved of the three UPR signal pathways. Upon a...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Zhang, Pengchao, Su, Chenhe, Jiang, Zhangtao, Zheng, Chunfu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286897/
https://ncbi.nlm.nih.gov/pubmed/27928013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02056-16
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