High Prevalence of Infectious Adeno-associated Virus (AAV) in Human Peripheral Blood Mononuclear Cells Indicative of T Lymphocytes as Sites of AAV Persistence

Seroepidemiology shows that infections with adeno-associated virus (AAV) are widespread, but diverse AAV serotypes isolated from humans or nonhuman primates have so far not been proven to be causes of human disease. In view of the increasing success of AAV-derived vectors in human gene therapy, defi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hüser, Daniela, Khalid, Dina, Lutter, Timo, Hammer, Eva-Maria, Weger, Stefan, Heßler, Melanie, Kalus, Ulrich, Tauchmann, Yvonne, Hensel-Wiegel, Karin, Lassner, Dirk, Heilbronn, Regine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286889/
https://ncbi.nlm.nih.gov/pubmed/27928011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02137-16
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