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Methylation Status of the Adeno-Associated Virus Type 2 (AAV2)

To analyze the methylation status of wild-type adeno-associated virus type 2 (AAV2), bisulfite PCR sequencing (BPS) of the packaged viral genome and its integrated form was performed and 262 of the total 266 CG dinucleotides (CpG) were mapped. In virion-packaged DNA, the ratio of the methylated cyto...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Tóth, Renáta, Mészáros, István, Hüser, Daniela, Forró, Barbara, Marton, Szilvia, Olasz, Ferenc, Bányai, Krisztián, Heilbronn, Regine, Zádori, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356613/
https://ncbi.nlm.nih.gov/pubmed/30634383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11010038
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