A Protective Role for Interleukin-1 Signaling during Mouse Adenovirus Type 1-Induced Encephalitis

Interleukin-1β (IL-1β), an inflammatory cytokine and IL-1 receptor ligand, has diverse activities in the brain. We examined whether IL-1 signaling contributes to the encephalitis observed in mouse adenovirus type 1 (MAV-1) infection, using mice lacking the IL-1 receptor (Il1r1(−/−) mice). Il1r1(−/−)...

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Vydáno v:J Virol
Hlavní autoři: Castro-Jorge, Luiza A., Pretto, Carla D., Smith, Asa B., Foreman, Oded, Carnahan, Kelly E., Spindler, Katherine R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286883/
https://ncbi.nlm.nih.gov/pubmed/27903802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02106-16
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