Contribution of a Single Host Genetic Locus to Mouse Adenovirus Type 1 Infection and Encephalitis

Susceptibility to mouse adenovirus type 1 (MAV-1) is mouse strain dependent; susceptible mice die from hemorrhagic encephalomyelitis. The MAV-1 susceptibility quantitative trait locus Msq1 accounts for ~40% of the phenotypic (brain viral load) variance that occurs between resistant BALB/c and suscep...

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Autors principals: Hsu, Tien-Huei, Althaus, Irene W., Foreman, Oded, Spindler, Katherine R.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Microbiology 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372963/
https://ncbi.nlm.nih.gov/pubmed/22647790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00131-12
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