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Two strategies to engineer flexible loops for improved enzyme thermostability
Flexible sites are potential targets for engineering the stability of enzymes. Nevertheless, the success rate of the rigidifying flexible sites (RFS) strategy is still low due to a limited understanding of how to determine the best mutation candidates. In this study, two parallel strategies were app...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286519/ https://ncbi.nlm.nih.gov/pubmed/28145457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41212 |
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