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A Role for Flexible Loops in Enzyme Catalysis
Triosephosphate isomerase (TIM), glycerol 3-phosphate dehydrogenase and orotidine 5'-monophosphate decarboxylase each use the binding energy from the interaction of phosphite dianion with a flexible phosphate gripper loop to activate a second, phosphodianion-truncated, substrate towards enzyme-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994964/ https://ncbi.nlm.nih.gov/pubmed/20951028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2010.09.005 |
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