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A Role for Flexible Loops in Enzyme Catalysis

Triosephosphate isomerase (TIM), glycerol 3-phosphate dehydrogenase and orotidine 5'-monophosphate decarboxylase each use the binding energy from the interaction of phosphite dianion with a flexible phosphate gripper loop to activate a second, phosphodianion-truncated, substrate towards enzyme-...

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Autors principals: Malabanan, M. Merced, Amyes, Tina L., Richard, John P.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994964/
https://ncbi.nlm.nih.gov/pubmed/20951028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2010.09.005
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