M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures

Microbicides are considered a promising strategy for preventing human immunodeficiency virus (HIV-1) transmission and disease. In this report, we first analyzed the antiviral activity of the miniCD4 M48U1 peptide formulated in hydroxyethylcellulose (HEC) hydrogel in activated peripheral blood mononu...

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Vydáno v:Sci Rep
Hlavní autoři: Musumeci, Giuseppina, Bon, Isabella, Lembo, David, Cagno, Valeria, Re, Maria Carla, Signoretto, Caterina, Diani, Erica, Lopalco, Lucia, Pastori, Claudia, Martin, Loïc, Ponchel, Gilles, Gibellini, Davide, Bouchemal, Kawthar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286506/
https://ncbi.nlm.nih.gov/pubmed/28145455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41018
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