Thermosensitive and Mucoadhesive Pluronic-Hydroxypropylmethylcellulose Hydrogel Containing the Mini-CD4 M48U1 Is a Promising Efficient Barrier against HIV Diffusion through Macaque Cervicovaginal Mucus

To be efficient, vaginal microbicide hydrogels should form a barrier against viral infections and prevent virus spreading through mucus. Multiple particle tracking was used to quantify the mobility of 170-nm fluorescently labeled COOH-modified polystyrene particles (COOH-PS) into thermosensitive hyd...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bouchemal, Kawthar, Aka-Any-Grah, Armelle, Dereuddre-Bosquet, Nathalie, Martin, Loïc, Lievin-Le-Moal, Vanessa, Le Grand, Roger, Nicolas, Valérie, Gibellini, Davide, Lembo, David, Poüs, Christian, Koffi, Armand, Ponchel, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356805/
https://ncbi.nlm.nih.gov/pubmed/25645853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03503-14
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