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Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein
Retinoids – derivatives of vitamin A – are important cell permeant signaling molecules that regulate gene expression through activation of nuclear receptors. P-glycoprotein (Pgp) and ABCG2 are plasma membrane efflux transporters affecting the tissue distribution of numerous structurally unrelated li...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286421/ https://ncbi.nlm.nih.gov/pubmed/28145501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41376 |
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