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Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein

Retinoids – derivatives of vitamin A – are important cell permeant signaling molecules that regulate gene expression through activation of nuclear receptors. P-glycoprotein (Pgp) and ABCG2 are plasma membrane efflux transporters affecting the tissue distribution of numerous structurally unrelated li...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tarapcsák, Szabolcs, Szalóki, Gábor, Telbisz, Ágnes, Gyöngy, Zsuzsanna, Matúz, Krisztina, Csősz, Éva, Nagy, Péter, Holb, Imre J., Rühl, Ralph, Nagy, László, Szabó, Gábor, Goda, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286421/
https://ncbi.nlm.nih.gov/pubmed/28145501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41376
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