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PD‐L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy
Pancreatic ductal adenocarcinoma (PDAC) is considered a non‐immunogenic tumor, and immune checkpoint inhibitor monotherapy lacks efficacy in this disease. Radiotherapy (RT) can stimulate the immune system. Here, we show that treatment of KPC and Pan02 murine PDAC cells with RT and gemcitabine upregu...
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| Veröffentlicht in: | EMBO Mol Med |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286375/ https://ncbi.nlm.nih.gov/pubmed/27932443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606674 |
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