Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma

We examined the prognostic value of programmed cell death-1 (PD-1) and its ligand (PD-L1) together with CD8+ tumor-infiltrating lymphocytes (TILs) and FOXP3+ Tregs in resectable pancreatic ductal adenocarcinoma (PDAC) samples treated with adjuvant chemotherapy. Whole-mount FFPE tissue sections from...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Diana, Angela, Wang, Lai Mun, D'Costa, Zenobia, Allen, Paul, Azad, Abul, Silva, Michael A., Soonawalla, Zahir, Liu, Stanley, McKenna, W. Gillies, Muschel, Ruth J., Fokas, Emmanouil
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173037/
https://ncbi.nlm.nih.gov/pubmed/27329602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10038
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