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Immune checkpoint blockade can synergize with radiation therapy, even in tumors resistant to checkpoint monotherapy

Immunotherapy has evolved as a new pillar of cancer treatment during the last decade. The main breakthrough was the development of immune checkpoint blocking (ICB) antibodies, which antagonize inhibitory receptors on T cells and their ligands and thus unleash the cellular immune system against the t...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Autor principal: Dörrie, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286364/
https://ncbi.nlm.nih.gov/pubmed/27965270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607219
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