Targeting phosphatidylserine synergizes with immune checkpoint blockade by inducing de novo tumor specific immunity

Eitemau Tebyg

• Antibody-mediated phosphatidylserine blockade significantly enhances the efficacy of downstream immune checkpoint inhibition in K1735 mouse melanoma
  gan: Huang, Xianming, et al.
  Cyhoeddwyd: (2014)
• Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment
  gan: Yopp, Adam, et al.
  Cyhoeddwyd: (2014)
• Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors
  gan: Gong, Jian, et al.
  Cyhoeddwyd: (2014)
• Targeting of phosphatidylserine by monoclonal antibodies reverses an immunosuppressive checkpoint inducing innate and specific anti-tumor responses
  gan: Gong, Jian, et al.
  Cyhoeddwyd: (2013)
• Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma
  gan: Freimark, Bruce D., et al.
  Cyhoeddwyd: (2016)