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Differential Binding of Mitochondrial Transcripts by MRB8170 and MRB4160 Regulates Distinct Editing Fates of Mitochondrial mRNA in Trypanosomes

A dozen mRNAs are edited by multiple insertions and/or deletions of uridine residues in the mitochondrion of Trypanosoma brucei. Several protein complexes have been implicated in performing this type of RNA editing, including the mitochondrial RNA-binding complex 1 (MRB1). Two paralogous novel RNA-b...

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Vydáno v:mBio
Hlavní autoři: Dixit, Sameer, Müller-McNicoll, Michaela, David, Vojtěch, Zarnack, Kathi, Ule, Jernej, Hashimi, Hassan, Lukeš, Julius
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285507/
https://ncbi.nlm.nih.gov/pubmed/28143982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02288-16
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