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Trypanosomes and the solution of a fifty years-mitochondrial calcium mystery

The ability of mitochondria to take up Ca(2+) was discovered 50 years ago. This calcium uptake, through a mitochondrial calcium uniporter (MCU), is important not only for the regulation of cellular ATP concentration but also for more complex pathways such as shaping Ca(2+) signals and activation of...

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Detalhes bibliográficos
Main Authors: Docampo, Roberto, Lukeš, Julius
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246531/
https://ncbi.nlm.nih.gov/pubmed/22088944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2011.10.007
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