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Trypanosome Letm1 Protein Is Essential for Mitochondrial Potassium Homeostasis

Letm1 is a conserved protein in eukaryotes bearing energized mitochondria. Hemizygous deletion of its gene has been implicated in symptoms of the human disease Wolf-Hirschhorn syndrome. Studies almost exclusively performed in opisthokonts have attributed several roles to Letm1, including maintaining...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hashimi, Hassan, McDonald, Lindsay, Stříbrná, Eva, Lukeš, Julius
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772241/
https://ncbi.nlm.nih.gov/pubmed/23893410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.495119
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