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Patient-specific models of microglia-mediated engulfment of synapses and neural progenitors

Engulfment of synapses and neural progenitor cells (NPCs) by microglia is critical for the development and maintenance of proper brain circuitry, and has been implicated in neurodevelopmental as well as neurodegenerative disease etiology. We have developed and validated models of these mechanisms by...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Sellgren, C M, Sheridan, S D, Gracias, J, Xuan, D, Fu, T, Perlis, R H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285468/
https://ncbi.nlm.nih.gov/pubmed/27956744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.220
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