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Dynamics of BAF- Polycomb Complex Opposition on Heterochromatin in Normal and Oncogenic States
The opposition between polycomb repressive complexes (PRC) and BAF (mSWI/SNF) complexes plays critical roles in development and disease. Mutations in the genes encoding BAF subunits contribute to over 20% of human malignancy, yet the underlying mechanisms remain unclear owing largely to a lack of as...
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| Veröffentlicht in: | Nat Genet |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5285326/ https://ncbi.nlm.nih.gov/pubmed/27941796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3734 |
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