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Retinal Dynamics Underlie Inverse-Agonist to Agonist Switch in Rhodopsin Activation
In seeking to understand G protein-coupled receptor (GPCR)-mediated signaling, X-ray and magnetic resonance approaches have played important roles—yet neither the protein dynamics nor the plasticity of GPCRs are amenable to study. Here we show that solid-state (2)H NMR relaxation elucidates picoseco...
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| Опубликовано в: : | Nat Struct Mol Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283944/ https://ncbi.nlm.nih.gov/pubmed/21278756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1982 |
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