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Retinal Dynamics Underlie Inverse-Agonist to Agonist Switch in Rhodopsin Activation

In seeking to understand G protein-coupled receptor (GPCR)-mediated signaling, X-ray and magnetic resonance approaches have played important roles—yet neither the protein dynamics nor the plasticity of GPCRs are amenable to study. Here we show that solid-state (2)H NMR relaxation elucidates picoseco...

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Foilsithe in:Nat Struct Mol Biol
Main Authors: Struts, Andrey V., Salgado, Gilmar F. J., Martínez-Mayorga, Karina, Brown, Michael F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283944/
https://ncbi.nlm.nih.gov/pubmed/21278756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1982
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