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Retinal Dynamics Underlie Inverse-Agonist to Agonist Switch in Rhodopsin Activation

In seeking to understand G protein-coupled receptor (GPCR)-mediated signaling, X-ray and magnetic resonance approaches have played important roles—yet neither the protein dynamics nor the plasticity of GPCRs are amenable to study. Here we show that solid-state (2)H NMR relaxation elucidates picoseco...

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Bibliografiska uppgifter
I publikationen:Nat Struct Mol Biol
Huvudupphovsmän: Struts, Andrey V., Salgado, Gilmar F. J., Martínez-Mayorga, Karina, Brown, Michael F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283944/
https://ncbi.nlm.nih.gov/pubmed/21278756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1982
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