Loading...

SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage

Myofibroblast differentiation is a key process in the pathogenesis of fibrotic diseases. Transforming growth factor-β(1) (TGF-β(1)) is a powerful inducer of myofibroblast differentiation and is implicated in pathogenesis of tissue fibrosis. This study was undertaken to determine the role of mitochon...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Bindu, Samik, Pillai, Vinodkumar B., Kanwal, Abhinav, Samant, Sadhana, Mutlu, Gökhan M., Verdin, Eric, Dulin, Nickolai, Gupta, Mahesh P.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283928/
https://ncbi.nlm.nih.gov/pubmed/27815257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00188.2016
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!