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Kupffer cells facilitate the acute effects of leptin on hepatic lipid metabolism
Leptin has potent effects on lipid metabolism in a number of peripheral tissues. In liver, an acute leptin infusion (~120 min) stimulates hepatic fatty acid oxidation (~30%) and reduces triglycerides (TG, ~40%), effects that are dependent on phosphoinositol-3-kinase (PI3K) activity. In the current s...
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| 出版年: | Am J Physiol Endocrinol Metab |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283880/ https://ncbi.nlm.nih.gov/pubmed/27827807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00250.2016 |
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