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Relationship between mutant SOD1 maturation and inclusion formation in cell models
A common property of Cu/Zn superoxide dismutase 1 (SOD1), harboring mutations associated with amyotrophic lateral sclerosis (ALS), is a high propensity to misfold and form abnormal aggregates. The aggregation of mutant SOD1 has been demonstrated in vitro, with purified proteins, in mouse models, in...
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| Publicado en: | J Neurochem |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283795/ https://ncbi.nlm.nih.gov/pubmed/27727458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13864 |
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